High-precision dosimetry
From UCL HEP PBT Wiki
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* <span style="color:#ff0000"> dnageometry </span>: This example simulates track structures of different charged particles within a simplified geometrical model of the DNA molecule in a cell nucleus. [http://www.chemguide.co.uk/organicprops/aminoacids/dna1.html Here] you can read more about the DNA structure. Simulated are 6109 DNA pairs with the following structures: double helix, nucleosome, chromatine fibres, chromatine fibre loops and chromosome territories. Proton beam is simulated using class '''G4ParticleGun'''. The physics processes are defined using class '''G4EmDNAPhysics'''. The output is a root ntuple with type of particle, type of physics process, energy deposit and step length for every simulation step. | * <span style="color:#ff0000"> dnageometry </span>: This example simulates track structures of different charged particles within a simplified geometrical model of the DNA molecule in a cell nucleus. [http://www.chemguide.co.uk/organicprops/aminoacids/dna1.html Here] you can read more about the DNA structure. Simulated are 6109 DNA pairs with the following structures: double helix, nucleosome, chromatine fibres, chromatine fibre loops and chromosome territories. Proton beam is simulated using class '''G4ParticleGun'''. The physics processes are defined using class '''G4EmDNAPhysics'''. The output is a root ntuple with type of particle, type of physics process, energy deposit and step length for every simulation step. | ||
| - | * <span style="color:#ff0000"> microbeam </span>: This example simulates the cellular irradiation beam line installed on the [http://www.cenbg.in2p3.fr/-AIFIRA-Home-?lang=en AIFIRA] electrostatic accelerator facility located at [http://www.cenbg.in2p3.fr/ CENBG], Bordeaux-Gradignan, France. This accelerator is mainly used to investigate the effects of low dose irradiation on living cells. A realistic cell phantom is obtained from confocal microscopy and from ion beam anlysis techniques. Alpha particles of 3 MeV are incident on this phantom. The output is dose deposited in the cell cytoplasm and in the cell nucleus. | + | * <span style="color:#ff0000"> microbeam </span>: This example simulates the cellular irradiation beam line installed on the [http://www.cenbg.in2p3.fr/-AIFIRA-Home-?lang=en AIFIRA] electrostatic accelerator facility located at [http://www.cenbg.in2p3.fr/ CENBG], Bordeaux-Gradignan, France. This accelerator is mainly used to investigate the effects of low dose irradiation on living cells. A realistic cell phantom is obtained from confocal microscopy and from ion beam anlysis techniques. Alpha particles of 3 MeV are incident on this phantom. The output among other things is the dose deposited in the cell cytoplasm and in the cell nucleus. |
== <span style="color:#000080"> How to run the tutorial </span> == | == <span style="color:#000080"> How to run the tutorial </span> == | ||
