Proton Calorimetry/Experimental Runs/2019/Apr12-15: Difference between revisions

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|46 || high || 221.06 || - || 3.2*10^9 ||  20.0 || p || DSC_199 || shoot through 5cm PMMA.  || -|
|46 || high || 221.06 || - || 3.2*10^9 ||  20.0 || p || DSC_199 || shoot through 5cm PMMA.  || -|
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|47 || high || 120.1 || - || 1.2*10^9 ||  13.4 || p || DSC_201 || about 10 cm range. exposure 0.1 sec  || -|
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|48 || high || 120.1 || - || 1.2*10^9 ||  14.4 || p || DSC_202 || about 10 cm range  || -|
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|49 || high || 120.1 || - || 1.2*10^9 ||  15.4 || p || DSC_203 || about 10 cm range  || -|
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|50 || high || 120.1 || - || 1.2*10^9 ||  16.5 || p || DSC_204 || about 10 cm range  || -|
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|51 || high || 120.1 || - || 1.2*10^9 ||  19.2 || p || DSC_205 || about 10 cm range  || -|
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|52 || high || 120.1 || - || 1.2*10^9 ||  20.9 || p || DSC_206 || about 10 cm range  || -|


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|53 || high || 120.42 || - || 3*10^8 ||  8.1 || He || DSC_207 || about 10 cm range. exposure 0.1 sec  || -|
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|54 || high || 120.4 || - || 3*10^8 ||  8.9 || He || DSC_208 || about 10 cm range  || -|
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|55 || high || 120.4 || - || 3*10^8 ||  10.4 || He || DSC_209 || about 10 cm range  || -|
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|56 || high || 120.4 || - || 3*10^8 ||  12 || He || DSC_210 || about 10 cm range  || -|


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|57 || high || 219.8 || - || 8*10^7 ||  4.7 || C || DSC_211 || about 10 cm range. exposure 0.1 sec  || -|
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|58 || high || 219.8 || - || 1.2*10^9 ||  6.4 || C || DSC_212 || about 10 cm range  || -|
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|59 || high || 219.8 || - || 1.2*10^9 ||  8.5 || C || DSC_213 || about 10 cm range  || -|
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|60 || high || 219.8 || - || 1.2*10^9 ||  10.3 || C || DSC_214 || about 10 cm range  || -|
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|61 || high || 219.8|| - || 1.2*10^9 ||  15. || C || DSC_215 || about 10 cm range  || -|
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|62 || high || 219.8 || - || 1.2*10^9 ||  20. || C || DSC_216 || about 10 cm range  || -|


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Revision as of 23:58, 12 April 2019

UPDATE THIS PAGE 2 night shifts with range calorimeter and single PMT module.

ISDI Sensor Instructions

General Sensor Configuration

Base Configuration is 14 x 1 Bit

Resolution is 1030 x 1536 pixels

For selecting pixel rows in centre: Use horizontal offset (ignore DVAL to activate field) and horizontal resolution


Increase number of frame buffers

To increase the number of frame buffers to the allowed maximum, start XCAP as administrator.

Select Capture/Sequence Capture/Video to Frame Buffers/Driver Assistant

Tick box in left field, then set number of frame buffers here.


Serial Terminal instructions for ISDI sensor

Find serial terminal in PIXCI(R) tab of sensor control software.

In Controls/Options: Make sure "Send string with CR" is selected. Should be default.

In Controls/Setup: Select Serial Port: Enabled. Baud rate has to be 115200

Set low full well mode using W000300000

Set high full well mode using W000300004

Read full well mode using R0003


Continuous Field buffer setting

This setting makes sure that the buffer is filled with a new frame as they come in. If this option is not selected the sensor and software will not be synchronised and we will record a lot of pitch black images.

Select Capture/Live Options//Live Mode/Live Video: Continuous All buffer capture


Equipment List

Item Notes
Network Hub Set in control room to take output from experimental room ethernet switcher. Control laptops connected via ethernet or 5GHz WiFi.
Control Laptop x3
DAQ Laptop In the experimental room
Ethernet Cable x 2 To connect DAQ PC to the network and the network hub to the network system.

Range Detector Experiment

UPDATE

RangeExperiment.png

Item Notes
Portable Enclosure Modified Big Zarges Waterproof Wheeled Equipment Case.

Features mount for scintillator and PMT, opening for beam, and ports for SHV, BNC, SMA, Camera Link cables.
Hole for sensor powering.
Mylar window with Al support mounted to internal face: approximately light-tight.

Scintillator stack 14 x 2 mm, 15 x 2.6 mm and 20 x 3 mm sheets in ascending order from the front/beam of the end of the scintillator. Sheet 21 not used. Sheet numbers from front to end (in beam direction): 30,29,28,27,26,22,19,18,17,15,14,13,10,7,25,24,23,20,16,12,11,9,8,6,5,4,3,2,1,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50.
ISDI CMOS sensor sensor pixel dimension: 1030 x 1536. NO optical grease between scintillator and sensor. Connected to DAQ PC via Camera Link cable.
DAQ desktop PC Controls sensor aquisition.
Gloves For handling scintillator

Experiment List

12–13th April

0. Find convenient beam intensity that does not saturate sensor: lowest clinical beam energy, smallest beam focus

1. Calibration of detector (highest clinical energy). Shoot from front and back of stack (we have a new entrance window at the back of the stack). Also calibrate at different focus sizes. Also test camera: focus on front of beam stack and centre of beam stack and compare.

2. Test focus (beam size) dependence: shoot pencil beam with ~10 cm range at different focus sizes

3. Measure WET of known blocks of plastic to calibrate range telescope using a pencil beam with ~10cm range. Lennart will check if he can find some PMMA slabs whose WET has been accurately measured. Ideally have some slabs between ~1mm and ~5cm WET thickness. We know that there are some PMMA slabs between 1mm and 5cm thickness, measured by Giulia Arico (OMA fellow). These measurements will be used to benchmark Laurent's reconstruction code. Use tightest beam focus.

4. Repeat 0.-3. with all available ions (protons, helium, carbon and oxgen)

5. Measure SOBP of protons. 10cm deep, 3cm plateau

6. Measure high proton energies (up to 250MeV) using PMMA absorber in front of range telescope.

7. Measure a couple of oxygen pencil beams (range shift) and SOBP

8. Disassemble detector.


13–14th April

0. Calibration for Carbon and calibration for helium at high full well mode. Also test reproducibility: Measure same pencil beam before and after re-assembling detector.

1. Measure Helium and Carbon SOBP through full range of both helium and Carbon. Similar as last time use real SOBP here. The SOBP measurement is useful to show what we are looking at. Measurements taken in step of 5cm PMMA slabs, as last time. Measure in high full well mode of detector. Beam intensities fixed to optimal output of detector. Check source switching time.

2. Repeat 1. with pencil beams but using the realistic beam intensities (2x10^8 for C12 and 2x10^7 for helium). Keep high full well mode for this (measurement useful as reference for intensity scaling of 1 later on).

2.5 Calibration for low full well mode (all following should be in that mode for highest accuracy on carbon fragments)

3. Repeat 2 but in low full well mode for best possible accuracy for helium beam and Carbon fragments. If signal gives too low resolution, find a good helium intensity for onward tests.

4. Use single pencil beam at highest energy (220MeV/u for largest fragment build up) and build small air gaps in the center of the "target": what is the smallest WET change we can see despite the Carbon fragments? What is the smallest lateral gap size we can see for each gap depth? Measure different beam focus sizes. At what depth should the air gap be placed?

->Test 4 different WET differences: 1mm, 2mm, 0.5cm, 1cm. Laterally, Lennart has to check what is the smallest PMMA slab they have two of. Use that to change the gap lateral size.

5. Potentially: Repeat 4 for lower energy. (could be left out)

6. Repeat 4 with different beam intensities (1 higher, 1 lower intensity). Question to be answered: how much helium do we need for this detector? Not needed if we use unrealistic beam intensities following measurement 2. Could also be left out and done in data processing. (not important for us)

7. Build an online moving air gap that was visible well in 4. Laurent has to set up a quick analysis to judge whether the change is visible. For this, build the PMMA slabs on top of the moving platform available at HIT. Lennart will prepare the remote controlling of the moving platform. Irradiate SOBP Plan and move platform across. Take a video of the central pixel signal. We could repeat this even and take a screen-video as we see the online changes when we take the full sensor in integral mode. Can use DSLR camera for this as well. Might be problematic because we can only see the horizontal movement from the side, i.e. we cannot make use of the focus of the camera. We should still be able to see a range mixing of parts of the beam going through the air gap and parts of it going through the full PMMA phantom.

8. Repeat 7 step-wise (6 steps of 0.5cm depending on the time available) and take full view of CMOS for both helium and Carbon. This sequence of images can be combined to a film (gif) in offline analysis.

9. Repeat 7 and 8 for the simple lung phantom. Interesting for publication and Joao has especially requested these measurements. Clarify what Joao is expecting to see. Movie of moving bragg curve with phantom an moving platform?

Measurement 4 and onward could be performed with realistic and/or unrealistic high helium intensity. The latter would give more resolution, but less realism. Lennart would say, that we see in 3 if our signal quality is good enough with the realistic beam and then decide what to do. We can always use high intensities and scale the signal down in data processing. Laurent believes that a helium intensity of 2*10^7 p/s will be observable in our detector but might be a faint signal. We need to decide on the fly if the resolution is ok or not. If not, use higher helium intensity.


14–15th April

0. Shoot-through calibration with 324 MeV/u Helium and Carbon beam (we can also use standard calibration energies, i.e. the highest clinical energies for helium and carbon), helium will be at an intensity of 7*10^8 (that is what was pre-set by the HIT engineers) it can be lowered if needed, but Lennart is still finding out how controlled that is (i.e if we get feedback on the intensity from the accelerator of if we are "blind").

1. Take full depth-dose curve of Carbon and helium. This would be an interesting test to see the signal from Helium at these high energies. Lennart is not sure if he will find enough PMMA with accurately measured WET but is working on it (we need 50 cm PMMA roughly).

2. Shoot through ADAM and measure both Helium and Carbon tail after Phantom. Aim at prostate close to rectum. Lennart chose the 324MeV/u according to a treatment plan. This carbon beam will stop in the prostate close to rectum.

3. Blow up the rectal balloon (2 steps: 50ml air, 75ml air), irradiate both helium and carbon. Do we see changes?

4. Reposition beam/rectal balloon if no change is visible. repeat 2 and 3 as needed.

5. Use no rectal balloon, aim at Prostate and fill Bladder in 2 steps: Do we see changes (no drastic changes expected)? Do only if plenty of time!

6. Aim at center of prostate and rotate phantom in 2 degree steps. Do we see changes? Some issue here is the hull of the phantom, which has a high gradient (curvature and dense material), so changes in range could be related mostly to that and the test might not be very realistic. Can also move phantom laterally as this measurement was recommended by Markus Stock from MedAustron. Could also be left out if under time pressure. Please be more specific about details of measurement: Alignment of phantom

7. Place the phantom vertically and aim at prostate. Measure both helium and carbon. Blow up rectum again (2 steps again) and show difference in range.

8. If still time/energy resources: more realistic lung phantom measurements. Lennart has yet to prepare a plan for these, as he only got the phantom recently. Alternatively, we could investigate the simple lung phantom from GSI, if we weren't able to do that in the second night shift.

9. There is a new pelvis phantom with fixed prostate available at HIT. It can be used for the measurement of horizontal displacements.


Experiment Log

Beam Tests

12–13th April

images from sensor: User/Public/Document/EPIX/XCAP/data/ images from dslr: User/Public/Document/Nikon/

  • full sensor area
  • shooting on back window
  • 0. finding the best beam intensity (proton)
  • Simon checking the intensity on pixels from dslr with nikon software
  • camera settings
    • exposure 1/2 sec
    • aperture f/3
    • ISO 200


Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N particles Spot size (mm) ion type DSLR file name Comments
N well mode Energy MeV/u Range particles Spot FWHM test dslr file name DSC_ comments
00 low None - None None - - background
01 high None - None None - - background
not saved from Laurent high None - None None - DSC_145 intensity check
02 high 221.06 - 2*10^9 8.1 p DSC_147 shoot through no degrader
03 high 221.06 - 3.2*10^9 11.1 p DSC_149 shoot through no degrader. from now on exposure time on dslr 0.2 sec
04 high 221.06 - 3.2*10^9 20.0 p DSC_150 shoot through no degrader.
05 low 221.06 - 1.2*10^9 20.0 p DSC_151 shoot through no degrader. exposure time back to 0.5 sec
06 low 221.06 - 1.2*10^9 11.1 p DSC_152 shoot through no degrader.
07 low 221.06 - 1.2*10^9 8.1 p DSC_153 shoot through no degrader.
08 high 220.51 - 8*10^8 4.9 He DSC_155 shoot through no degrader. exposure 0.1 sec
09 high 220.51 - 8*10^8 8.1 He DSC_156 shoot through no degrader.
10 high 220.51 - 8*10^8 10.1 He DSC_157 shoot through no degrader.
11 high 430.1 - 8*10^7 3.4 C DSC_159 shoot through no degrader. ripple filter 3mm
12 high 430.1 - 8*10^7 7.8 C DSC_160 shoot through no degrader. ripple filter 3mm
13 high 430.1 - 8*10^7 20 C DSC_161 shoot through no degrader.ripple filter 3mm. exposure 0.5 sec
14 high 430.1 - 8*10^7 3.4 C DSC_162 shoot through. PMMA 5 cm
15 high 430.1 - 8*10^7 7.8 C DSC_163 shoot through. PMMA 5cm
16 high 430.1 - 8*10^7 20 C DSC_164 shoot through. PMMA 5cm
17 high 220.51 - 8*10^8 4.9 He DSC_165 shoot through. PMMA 5 cm. exposure 0.1
18 high 220.51 - 8*10^8 8.1 He DSC_166 shoot through. PMMA 5cm
19 high 220.51 - 8*10^8 10.1 He DSC_167 shoot through. PMMA 5cm
20 high 221.06 - 3.2*10^9 8.1 p DSC_168 shoot through. PMMA 5 cm. exposure 0.2
21 high 221.06 - 3.2*10^9 11.1 p DSC_169 shoot through. PMMA 5cm
22 high 221.06 - 3.2*10^9 20 p DSC_170 shoot through. PMMA 5cm
23 high 430.1 - 8*10^7 3.4 C DSC_172 shoot through. no absorber. exposure 0.1
24 high 430.1 - 8*10^7 7.8 C DSC_173 shoot through. no absorber
25 high 430.1 - 8*10^7 20 C DSC_175 shoot through. no absorber. exposure 0.2 sec
  • the case has been ROTEATED around. We now shoot on the FRONT window
Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N particles Spot size (mm) ion type DSLR file name Comments
N well mode Energy MeV/u Range particles Spot FWHM test dslr file name DSC_ comments
26 high 60.9 - 6*10^8 26.3 p DSC_176 front window Intensity chack. exposure 0.5 sec
27 high 60.8 - 2*10^8 15.4 He DSC_178 front window Intensity chack. exposure 0.5 sec
28 high 110.6 - 2*10^7 8.4 C DSC_180 front window Intensity chack. exposure 0.5 sec
29 high 430.1 - 8*10^7 3.4 C DSC_181 front window shoot through. no absorber. exposure 0.2 sec
30 high 430.1 - 8*10^7 7.8 C DSC_182 shoot through. no absorber
31 high 430.1 - 8*10^7 20 C DSC_183 shoot through. no absorber.
32 high 221.06 - 3.2*10^9 20.0 p DSC_184 shoot through no degrader.
33 high 221.06 - 3.2*10^9 11.1 p DSC_185 shoot through no degrader.
34 high 221.06 - 3.2*10^9 8.1 p DSC_186 shoot through no degrader.
35 high 220.51 - 8*10^8 4.9 He DSC_187 shoot through no degrader. exposure 0.1 sec
36 high 220.51 - 8*10^8 8.1 He DSC_188 shoot through no degrader.
37 high 220.51 - 8*10^8 10.1 He DSC_190 shoot through no degrader.
38 high 220.51 - 8*10^8 4.9 He DSC_191 shoot through 5cm PMMA. exposure 0.1 sec
39 high 220.51 - 8*10^8 8.1 He DSC_192 shoot through 5cm PMMA.
40 high 220.51 - 8*10^8 10.1 He DSC_193 shoot through 5cm PMMA.
41 high 430.1 - 8*10^7 3.4 C DSC_194 front window shoot through. 5cm PMMA. exposure 0.2 sec
42 high 430.1 - 8*10^7 7.8 C DSC_195 shoot through. 5cm PMMA
43 high 430.1 - 8*10^7 20 C DSC_196 shoot through. 5cm PMMA.
44 high 221.06 - 3.2*10^9 8.1 p DSC_197 shoot through 5cm PMMA. exposure 0.2 sec
45 high 221.06 - 3.2*10^9 11.1 p DSC_198 shoot through 5cm PMMA.
46 high 221.06 - 3.2*10^9 20.0 p DSC_199 shoot through 5cm PMMA.
47 high 120.1 - 1.2*10^9 13.4 p DSC_201 about 10 cm range. exposure 0.1 sec
48 high 120.1 - 1.2*10^9 14.4 p DSC_202 about 10 cm range
49 high 120.1 - 1.2*10^9 15.4 p DSC_203 about 10 cm range
50 high 120.1 - 1.2*10^9 16.5 p DSC_204 about 10 cm range
51 high 120.1 - 1.2*10^9 19.2 p DSC_205 about 10 cm range
52 high 120.1 - 1.2*10^9 20.9 p DSC_206 about 10 cm range
53 high 120.42 - 3*10^8 8.1 He DSC_207 about 10 cm range. exposure 0.1 sec
54 high 120.4 - 3*10^8 8.9 He DSC_208 about 10 cm range
55 high 120.4 - 3*10^8 10.4 He DSC_209 about 10 cm range
56 high 120.4 - 3*10^8 12 He DSC_210 about 10 cm range
57 high 219.8 - 8*10^7 4.7 C DSC_211 about 10 cm range. exposure 0.1 sec
58 high 219.8 - 1.2*10^9 6.4 C DSC_212 about 10 cm range
59 high 219.8 - 1.2*10^9 8.5 C DSC_213 about 10 cm range
60 high 219.8 - 1.2*10^9 10.3 C DSC_214 about 10 cm range
61 high 219.8 - 1.2*10^9 15. C DSC_215 about 10 cm range
62 high 219.8 - 1.2*10^9 20. C DSC_216 about 10 cm range




copy paste for convenience from Nov2018

Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N particles Spot size (mm) ion type DSLR file name Comments
N well mode Energy MeV/u Range particles Spot FWHM test dslr file name
00 low None - None None - background
01 low 50.57 22.9 10^8 18.6 He low energy, low intensity

Carbon ion beam

full sensor

Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N particles Spot size (mm) Test type Comments Thumbnail
N well mode Energy MeV/u Range particles Spot FWHM test comments
44 high None - None None - background

Proton beam

full sensor

Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N particles Spot size (mm) Test type Comments Thumbnail
N well mode Energy MeV/u Range particles Spot FWHM test comments
79 high None - None None - background

14–15th April

Beam focus ranges from step 1 (smallest) to step 4 (of 6).

Helium ion beam

full sensor area

Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N ions /s Spot size (mm) Test type Comments Thumbnail
N well mode Energy MeV/u Range ions/s Spot FWHM test comments
00 high None - None None - background
01 high 50.57 22.9 8x10^8 18.6 He low energy, max clinical intensity

Mixed Helium and Carbon ions beam

full sensor

Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N particles Spot size (mm) Test type Comments Thumbnail
N well mode Energy MeV/u Range particles Spot FWHM test comments
09 high 182.32 - 222.31 74.4 - 104.5 - 5.5 - 4.7 C Real Clinical SOBP, 6 pixel rows (512 offset), 100mm distal edge using clinical weighting with approx. equal time to deliver each layer with single on-axis spot.