Proton Calorimetry/Experimental Runs/2019/Apr12-15

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3 night shifts with range calorimeter + SDLR

Experiment Equipment

Item Notes
Network Hub Set in control room to take output from experimental room ethernet connection. Control laptops connected via 5GHz WiFi.
Control Laptop x3 2x remote control for sensor and sdlr, 1 for notes
DAQ laptop
Ethernet Cable x 2 To connect DAQ laptop to network in the experimental room, network hub to network in control room.
Portable Enclosure Modified Big Zarges Waterproof Wheeled Equipment Case.

Features mount for scintillator and PMT, opening for beam, and ports for SHV, BNC, SMA, Camera Link cables.
Hole for sensor powering.
Mylar window with Al support mounted to internal face: approximately light-tight.

Scintillator stack 14 x 2 mm, 15 x 2.6 mm and 20 x 3 mm sheets in ascending order from the front/beam of the end of the scintillator. Sheet 21 not used. Sheet numbers from front to end (in beam direction): 30,29,28,27,26,22,19,18,17,15,14,13,10,7,25,24,23,20,16,12,11,9,8,6,5,4,3,2,1,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50.
ISDI CMOS sensor sensor pixel dimension: 1030 x 1536. NO optical grease between scintillator and sensor. Connected to DAQ PC via Camera Link cable.
DAQ desktop PC Controls sensor aquisition.
Gloves For handling scintillator

Range Detector Experiment

RangeExperiment.png

ISDI Sensor Instructions

General Sensor Configuration Base Configuration is 14 x 1 Bit Resolution is 1030 x 1536 pixels For selecting pixel rows in centre: Use horizontal offset (ignore DVAL to activate field) and horizontal resolution

Increase number of frame buffers To increase the number of frame buffers to the allowed maximum, start XCAP as administrator. Select Capture/Sequence Capture/Video to Frame Buffers/Driver Assistant Tick box in left field, then set number of frame buffers here.

Serial Terminal instructions for ISDI sensor Find serial terminal in PIXCI(R) tab of sensor control software. In Controls/Options: Make sure "Send string with CR" is selected. Should be default. In Controls/Setup: Select Serial Port: Enabled. Baud rate has to be 115200 Set low full well mode using W000300000 Set high full well mode using W000300004 Read full well mode using R0003

Continuous Field buffer setting This setting makes sure that the buffer is filled with a new frame as they come in. If this option is not selected the sensor and software will not be synchronised and we will record a lot of pitch black images. Select Capture/Live Options//Live Mode/Live Video: Continuous All buffer capture

Experiment List

12–13th April

  1. Find convenient beam intensity that does not saturate sensor: lowest clinical beam energy, smallest beam focus
  2. Calibration of detector (highest clinical energy). Shoot from front and back of stack (we have a new entrance window at the back of the stack). Also calibrate at different focus sizes. Also test camera: focus on front of beam stack and centre of beam stack and compare.
  3. Test focus (beam size) dependence: shoot pencil beam with ~10 cm range at different focus sizes
  4. Measure WET of known blocks of plastic to calibrate range telescope using a pencil beam with ~10cm range. Lennart will check if he can find some PMMA slabs whose WET has been accurately measured. Ideally have some slabs between ~1mm and ~5cm WET thickness. We know that there are some PMMA slabs between 1mm and 5cm thickness, measured by Giulia Arico (OMA fellow). These measurements will be used to benchmark Laurent's reconstruction code. Use tightest beam focus.
  5. Repeat 0.-3. with all available ions (protons, helium, carbon and oxgen)
  6. Measure SOBP of protons. 10cm deep, 3cm plateau
  7. Measure high proton energies (up to 250MeV) using PMMA absorber in front of range telescope.
  8. Measure a couple of oxygen pencil beams (range shift) and SOBP
  9. Disassemble detector.

13–14th April

  1. Shoot-through calibration for Helium and Carbon: 430.1MeV/u Carbon 30cm range, He 220.5MeV/u 30cm range.
    1. High full-well mode C Intensity: 8*10^7; He Intensity: 8x10^8.
    2. Low full well mode C Intensity: 3*10^7; He Intensity 3*10^8.
    3. Rotate detector; repeat.
  2. Carbon and Helium SOBP and single energy pencil beam:
    1. 2 Gy SOBP Carbon, Helium mix keep same intensity here and scale down later in data processing.
    2. Carbon and Helium Intensities both 8*10^7 (low Helium intensity!). Both high and low full well modes. Only measure low full well as sensor starts to come out of saturation.
    3. Carbon SOBP max range ~9cm (plateau 3cm longitudinal, 3x3cm2 lateral), He SOBP max range ~27 cm.
    4. Repeat with 220MeV/u pencil beam (C 10cm, He 30 cm).
  3. Add PMMA blocks, repeat previous measurement. 24 measurements; 5 changes in room. (5+5+5+2+2cm PMMA blocks, 19cm PMMA in total). Both high and low full well mode.
  1. Variable air gap measurements:
    1. 5cm PMMA, air gap, remaining PMMA absorber; total thickness of 18.8cm.
    2. Vary air gap width: 0mm, 1mm, 2mm, 5mm.
    3. Vary air gap depth: 1mm, 2mm, 5mm.
    4. Upstream PMMA absorber 5cm; downstream PMMA absorber varies from 13.3cm to 13.7cm.
    5. 24 measurements, 12 absorber changes.
    6. For 5mm x 5mm gap, adjust focal spot size.
    7. Energy 220 MeV/u for both; intensity 8*10^7 for both; use focus setting 3 (8.5mm for Carbon; 8.1mm for Helium).

-> For 1mm exclusively do field single energy layer SOBP impinging on 1mm gap placed in center of the field, that covers half the field (show that half the spots are out), take fotograph. Could be interesting to compare to CNAO later (they did the same)

-> take 0.2cm gap and move it to the other side of (just before last 5cm PMMA)



6. Moving platform measurments:

->(a) Take visible gap from 5: I would go for something we know will be distinguishable: 0.2cm? make 0.2x0.2cm2 slit and move it across while irradiating SOBP plan for both Carbon and helium? alignment difficult in terms of aligning the motion with the spill.

->(b) Same for pencil beam.

-> Repeat 6 (b) stepwise in 0.5 mm steps to create a .gif later. Alternative: Do a off center airgap and shoot single pencil beams scanned.

-> Take 2 mm oval shaped gap and repeat 6(a).

(-> Joao asked to maybe repeat 6 (a) with the steps.)


7. Lung phantom measurements only(!) if enough time. Take lung phantom, place it on height adjustable table, place tumor in beam (180 MeV/u C and He), lift it by 0.5 cm

14–15th April

  1. Shoot-through calibration with 324 MeV/u Helium and Carbon beam (we can also use standard calibration energies, i.e. the highest clinical energies for helium and carbon), helium will be at an intensity of 7*10^8 (that is what was pre-set by the HIT engineers) it can be lowered if needed, but Lennart is still finding out how controlled that is (i.e if we get feedback on the intensity from the accelerator of if we are "blind").
  2. Take full depth-dose curve of Carbon and helium. This would be an interesting test to see the signal from Helium at these high energies. Lennart is not sure if he will find enough PMMA with accurately measured WET but is working on it (we need 50 cm PMMA roughly).
  3. Shoot through ADAM and measure both Helium and Carbon tail after Phantom. Aim at prostate close to rectum. Lennart chose the 324MeV/u according to a treatment plan. This carbon beam will stop in the prostate close to rectum.
  4. Blow up the rectal balloon (2 steps: 50ml air, 75ml air), irradiate both helium and carbon. Do we see changes?
  5. Reposition beam/rectal balloon if no change is visible. repeat 2 and 3 as needed.
  6. Use no rectal balloon, aim at Prostate and fill Bladder in 2 steps: Do we see changes (no drastic changes expected)? Do only if plenty of time!
  7. Aim at center of prostate and rotate phantom in 2 degree steps. Do we see changes? Some issue here is the hull of the phantom, which has a high gradient (curvature and dense material), so changes in range could be related mostly to that and the test might not be very realistic. Can also move phantom laterally as this measurement was recommended by Markus Stock from MedAustron. Could also be left out if under time pressure. Please be more specific about details of measurement: Alignment of phantom
  8. Place the phantom vertically and aim at prostate. Measure both helium and carbon. Blow up rectum again (2 steps again) and show difference in range.
  9. If still time/energy resources: more realistic lung phantom measurements. Lennart has yet to prepare a plan for these, as he only got the phantom recently. Alternatively, we could investigate the simple lung phantom from GSI, if we weren't able to do that in the second night shift.
  10. There is a new pelvis phantom with fixed prostate available at HIT. It can be used for the measurement of horizontal displacements.


Range Detector Experiment

Range calorimeter measurements with ISDI sensor + scintillator stack.

12–13th April

images from sensor: User/Public/Document/EPIX/XCAP/data/ images from dslr: User/Public/Document/Nikon/

  • full sensor area
  • shooting on back window
  • 0. finding the best beam intensity (proton)
  • Simon checking the intensity on pixels from dslr with nikon software
  • camera settings
    • exposure 1/2 sec
    • aperture f/3
    • ISO 200
Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N particles Spot size (mm) ion type DSLR file name Comments
N well mode Energy MeV/u Range particles Spot FWHM test dslr file name DSC_ comments
00 low None - None None - - background
01 high None - None None - - background
not saved from Laurent high None - None None - DSC_145 intensity check
02 high 221.06 - 2*10^9 8.1 p DSC_147 shoot through no degrader
03 high 221.06 - 3.2*10^9 11.1 p DSC_149 shoot through no degrader. from now on exposure time on dslr 0.2 sec
04 high 221.06 - 3.2*10^9 20.0 p DSC_150 shoot through no degrader.
05 low 221.06 - 1.2*10^9 20.0 p DSC_151 shoot through no degrader. exposure time back to 0.5 sec
06 low 221.06 - 1.2*10^9 11.1 p DSC_152 shoot through no degrader.
07 low 221.06 - 1.2*10^9 8.1 p DSC_153 shoot through no degrader.
08 high 220.51 - 8*10^8 4.9 He DSC_155 shoot through no degrader. exposure 0.1 sec
09 high 220.51 - 8*10^8 8.1 He DSC_156 shoot through no degrader.
10 high 220.51 - 8*10^8 10.1 He DSC_157 shoot through no degrader.
11 high 430.1 - 8*10^7 3.4 C DSC_159 shoot through no degrader. ripple filter 3mm
12 high 430.1 - 8*10^7 7.8 C DSC_160 shoot through no degrader. ripple filter 3mm
13 high 430.1 - 8*10^7 20 C DSC_161 shoot through no degrader.ripple filter 3mm. exposure 0.5 sec
14 high 430.1 - 8*10^7 3.4 C DSC_162 shoot through. PMMA 5 cm
15 high 430.1 - 8*10^7 7.8 C DSC_163 shoot through. PMMA 5cm
16 high 430.1 - 8*10^7 20 C DSC_164 shoot through. PMMA 5cm
17 high 220.51 - 8*10^8 4.9 He DSC_165 shoot through. PMMA 5 cm. exposure 0.1
18 high 220.51 - 8*10^8 8.1 He DSC_166 shoot through. PMMA 5cm
19 high 220.51 - 8*10^8 10.1 He DSC_167 shoot through. PMMA 5cm
20 high 221.06 - 3.2*10^9 8.1 p DSC_168 shoot through. PMMA 5 cm. exposure 0.2
21 high 221.06 - 3.2*10^9 11.1 p DSC_169 shoot through. PMMA 5cm
22 high 221.06 - 3.2*10^9 20 p DSC_170 shoot through. PMMA 5cm
23 high 430.1 - 8*10^7 3.4 C DSC_172 shoot through. no absorber. exposure 0.1
24 high 430.1 - 8*10^7 7.8 C DSC_173 shoot through. no absorber
25 high 430.1 - 8*10^7 20 C DSC_175 shoot through. no absorber. exposure 0.2 sec
  • the case has been ROTEATED around. We now shoot on the FRONT window
Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N particles Spot size (mm) ion type DSLR file name Comments
N well mode Energy MeV/u Range particles Spot FWHM test dslr file name DSC_ comments
26 high 60.9 - 6*10^8 26.3 p DSC_176 front window Intensity chack. exposure 0.5 sec
27 high 60.8 - 2*10^8 15.4 He DSC_178 front window Intensity chack. exposure 0.5 sec
28 high 110.6 - 2*10^7 8.4 C DSC_180 front window Intensity chack. exposure 0.5 sec
29 high 430.1 - 8*10^7 3.4 C DSC_181 front window shoot through. no absorber. exposure 0.2 sec
30 high 430.1 - 8*10^7 7.8 C DSC_182 shoot through. no absorber
31 high 430.1 - 8*10^7 20 C DSC_183 shoot through. no absorber.
32 high 221.06 - 3.2*10^9 20.0 p DSC_184 shoot through no degrader.
33 high 221.06 - 3.2*10^9 11.1 p DSC_185 shoot through no degrader.
34 high 221.06 - 3.2*10^9 8.1 p DSC_186 shoot through no degrader.
35 high 220.51 - 8*10^8 4.9 He DSC_187 shoot through no degrader. exposure 0.1 sec
36 high 220.51 - 8*10^8 8.1 He DSC_188 shoot through no degrader.
37 high 220.51 - 8*10^8 10.1 He DSC_190 shoot through no degrader.
38 high 220.51 - 8*10^8 4.9 He DSC_191 shoot through 5cm PMMA. exposure 0.1 sec
39 high 220.51 - 8*10^8 8.1 He DSC_192 shoot through 5cm PMMA.
40 high 220.51 - 8*10^8 10.1 He DSC_193 shoot through 5cm PMMA.
41 high 430.1 - 8*10^7 3.4 C DSC_194 front window shoot through. 5cm PMMA. exposure 0.2 sec
42 high 430.1 - 8*10^7 7.8 C DSC_195 shoot through. 5cm PMMA
43 high 430.1 - 8*10^7 20 C DSC_196 shoot through. 5cm PMMA.
44 high 221.06 - 3.2*10^9 8.1 p DSC_197 shoot through 5cm PMMA. exposure 0.2 sec
45 high 221.06 - 3.2*10^9 11.1 p DSC_198 shoot through 5cm PMMA.
46 high 221.06 - 3.2*10^9 20.0 p DSC_199 shoot through 5cm PMMA.
47 high 120.1 - 1.2*10^9 13.4 p DSC_201 about 10 cm range. exposure 0.1 sec
48 high 120.1 - 1.2*10^9 14.4 p DSC_202 about 10 cm range
49 high 120.1 - 1.2*10^9 15.4 p DSC_203 about 10 cm range
50 high 120.1 - 1.2*10^9 16.5 p DSC_204 about 10 cm range
51 high 120.1 - 1.2*10^9 19.2 p DSC_205 about 10 cm range
52 high 120.1 - 1.2*10^9 20.9 p DSC_206 about 10 cm range
53 high 120.42 - 3*10^8 8.1 He DSC_207 about 10 cm range. exposure 0.1 sec
54 high 120.4 - 3*10^8 8.9 He DSC_208 about 10 cm range
55 high 120.4 - 3*10^8 10.4 He DSC_209 about 10 cm range
56 high 120.4 - 3*10^8 12 He DSC_210 about 10 cm range
57 high 219.8 - 8*10^7 4.7 C DSC_211 about 10 cm range. exposure 0.1 sec
58 high 219.8 - 8*10^7 6.4 C DSC_212 about 10 cm range
59 high 219.8 - 8*10^7 8.5 C DSC_213 about 10 cm range
60 high 219.8 - 8*10^7 10.3 C DSC_214 about 10 cm range
61 high 219.8 - 8*10^7 15. C DSC_215 about 10 cm range
62 high 219.8 - 8*10^7 20. C DSC_216 about 10 cm range
63 high 219.8 - 1.2*10^9 4.7 C DSC_217 2mm PMMA absorber. exposure 0.1 sec
64 high 120.42 - 3*10^8 8.1 He DSC_218 2mm PMMA absorber. exposure 0.1 sec
65 high 120.1 - 1.2*10^9 13.4 p DSC_219 2mm PMMA absorber. exposure 0.1 sec
66 high 120.1 - 1.2*10^9 13.4 p DSC_220 1mm PMMA absorber. exposure 0.1 sec
67 high 219.8 - 8*10^7 4.7 C DSC_222 1mm PMMA absorber. exposure 0.1 sec
68 high 120.42 - 3*10^8 8.1 He DSC_223 1mm PMMA absorber. exposure 0.1 sec
69 high 120.42 - 3*10^8 8.1 He DSC_224 5mm PMMA absorber. exposure 0.1 sec
70 high 120.1 - 1.2*10^9 13.4 p DSC_225 5mm PMMA absorber. exposure 0.1 sec
71 high 219.8 - 8*10^7 4.7 C DSC_226 5mm PMMA absorber. exposure 0.1 sec
72 high 219.8 - 8*10^7 4.7 C DSC_227 10mm PMMA absorber. exposure 0.1 sec
73 high 120.42 - 3*10^8 8.1 He DSC_228 10mm PMMA absorber. exposure 0.1 sec
74 high 120.1 - 1.2*10^9 13.4 p DSC_229 10mm PMMA absorber. exposure 0.1 sec
75 high 120.1 - 1.2*10^9 13.4 p DSC_230 20mm PMMA absorber. exposure 0.1 sec
76 high 219.8 - 8*10^7 4.7 C - 20mm PMMA absorber. DSLR out of charge
77 high 120.42 - 3*10^8 8.1 He - 20mm PMMA absorber. -
78 high 120.42 - 3*10^8 8.1 He - 50mm PMMA absorber. -
79 high 120.1 - 1.2*10^9 13.4 p - 50mm PMMA absorber.
80 high 219.8 - 8*10^7 4.7 C - 50mm PMMA absorber.
81 high max 116.85 min 98.27 - 1.2*10^9 13.7 - 16 p - SOBP no absorber. n. of steps in the file sent by email at 3.10 am on 13 Apr 2019. sensor: 10 pix in the center
82 high - - - - - - background. sensor 10 px in the center
83 high 221.1 - 1.2*10^9 8.1 p - 20cm (5 + 5 + 5 + 2 + 2 + 1 cm) PMMA absorber.
84 high 215.3 - 1.2*10^9 8.1 p - 20cm PMMA absorber.
85 high 210.1 - 1.2*10^9 8.1 p - 20cm PMMA absorber.
86 high 205.5 - 1.2*10^9 8.2 p - 20cm PMMA absorber.
87 high 200.1 - 1.2*10^9 8.4 p - 20cm PMMA absorber.
88 high 200.1 - 1.2*10^9 8.4 p - 12cm (5 + 5 + 2 cm) PMMA absorber.
89 high 195.3 - 1.2*10^9 8.6 p - 12cm PMMA absorber.
90 high 190.5 - 1.2*10^9 8.0 p - 12cm PMMA absorber.
91 high 185.5 - 1.2*10^9 9.1 p - 12cm PMMA absorber.
92 high 180.5 - 1.2*10^9 9.4 p - 12cm PMMA absorber.
93 high 175.3 - 1.2*10^9 9.7 p - 12cm PMMA absorber.
94 high 170.6 - 1.2*10^9 9.9 p - 12cm PMMA absorber.
95 high 165.4 - 1.2*10^9 10.3 p - 12cm PMMA absorber.
96 high 160.1 - 1.2*10^9 10.6 p - 12cm PMMA absorber.
97 high 155.3 - 1.2*10^9 10.9 p - 12cm PMMA absorber.
98 high 155.3 - 1.2*10^9 10.9 p - 5cm PMMA absorber.
99 high 150.4 - 1.2*10^9 11.2 p - 5cm PMMA absorber.
100 high 145.5 - 1.2*10^9 11.5 p - 5cm PMMA absorber.
101 high 140.4 - 1.2*10^9 11.8 p - 5cm PMMA absorber.
102 high 135.2 - 1.2*10^9 12.2 p - 5cm PMMA absorber.
103 high 130.5 - 1.2*10^9 12.5 p - 5cm PMMA absorber.
104 high 125.1 - 1.2*10^9 12.9 p - 5cm PMMA absorber.
105 high 120.1 - 1.2*10^9 13.4 p - 5cm PMMA absorber.
106 high 115.6 - 1.2*10^9 13.8 p - 5cm PMMA absorber.
107 high 110.2 - 1.2*10^9 14.4 p - 5cm PMMA absorber.
108 high 105.4 - 1.2*10^9 15. p - 5cm PMMA absorber.maybe missed
109 high 105.4 - 1.2*10^9 15. p - no absorber.maybe missed
110 high 100.5 - 1.2*10^9 15.7 p - no absorber.maybe missed
111 high 95.3 - 1.2*10^9 16.5 p - no absorber. maybe missed. Lairent saved as 111 a copy of 112
112 high 90.7 - 1.2*10^9 17.4 p - no absorber. Laurent saved for sure this
113 high 85.1 - 1.2*10^9 18.5 p - no absorber. maybe missed
114 high 80.04 - 1.2*10^9 19.8 p - no absorber. maybe missed. Laurent saved as 114 a copy of 115
115 high 48.1 - 1.2*10^9 32.4 p - no absorber. Laurent surely saved this


  • OXYGEN
Run number Full Well Mode Beam Energy (MeV/u) Range (estimated) N particles Spot size (mm) ion type DSLR file name Comments
N well mode Energy MeV/u Range particles Spot FWHM test dslr file name DSC_ comments
116 high 231.4 - 4.*10^7 4.3 O - Intensity test 5cm absorber (absorber n 3)
117 low 231.4 - 4.*10^7 4.3 O - Intensity test 5cm absorber (absorber n 3)
118 low 231.4 - 1.5*10^7 4.3 O - Intensity test 5cm absorber (absorber n 3)
119 low 231.4 - 2.5*10^7 4.3 O - Intensity test 5cm absorber(absorber n 3)
120 low 430.32 - 2.5*10^7 2.7 O - shoot-through with 5cm absorber (absorber n 3)
121 low 430.32 - 2.5*10^7 2.7 O - shoot-through no absorber
122 low 261.1 - 2.5*10^7 3.9 O - range calibration no absorber
123 low 245.7 - 2.5*10^7 4.1 O - range calibration no absorber
124 low 231.4 - 1.5*10^7 4.3 O - range calibration no absorber
125 low 214.7 - 1.5*10^7 4.5 O - range calibration no absorber
126 low 200.9 - 2.5*10^7 4.8 O - range calibration no absorber
127 low 200.9 - 1.5*10^7 4.8 O - range calibration no absorber
128 low 184.5 - 1.5*10^7 5.2 O - range calibration no absorber
129 low 169 - 1.5*10^7 5.6 O - range calibration no absorber
130 low 150.2 - 1.5*10^7 6.3 O - range calibration no absorber
131 low 124.7 - 1.5*10^7 7.5 O - range calibration no absorber
132 low 103.8 - 1.5*10^7 8.8 O - range calibration no absorber
133 low 233 - 1.5*10^7 4.3 O - range calibration no absorber
134 low 234.62 - 1.5*10^7 4.2 O - range calibration no absorber
135 low 236.24 - 1.5*10^7 4.2 O - range calibration no absorber
136 low 237.83 - 1.5*10^7 4.2 O - range calibration no absorber
137 low 239.42 - 1.5*10^7 4.2 O - range calibration no absorber
138 low 241 - 1.5*10^7 4.2 O - range calibration no absorber
139 low 242.58 - 1.5*10^7 4.1 O - range calibration no absorber
140 low 244.15 - 1.5*10^7 4.1 O - range calibration no absorber
141 low 245.71 - 1.5*10^7 4.1 O - range calibration no absorber
142 low 247.26 - 1.5*10^7 4.1 O - range calibration no absorber
143 low 248.83 - 1.5*10^7 4.1 O - range calibration no absorber
144 low 252.0 - 1.5*10^7 4.0 O - range calibration no absorber
145 low 253.54 - 1.5*10^7 4.0 O - range calibration no absorber
146 low - - - - - - background