ELogs/JoeBateman: Difference between revisions

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=== MC Simulations ===
=== MC Simulations ===
==== Dose Reconstruction ====
==== Dose Reconstruction ====
* Reconstructing UCLH 04-5/2024 QuADProBe Beam Test Dose Distributions - mainly SOBP and 3x3x7 cm^3 box field using TOPAS (via CVMFS on HEP Cluster) and FRED (locally for now, but eventually over Hypatia GPU cluster).
* If looking to use FRED - need to get installed on Plus1 or over Hypatia cluster for GPU processing capabilities (need training in Hypatia cluster first)
* Disagreement between depth dose curve for FRED and TOPAS (using default physics settings) - agreement in plateau but FRED has sharper and higher Bragg Peak
** Only an issue when there's an energy spread in the pencil beam (i.e. PDD's agree almost perfectly for a mono energetic beam with no spread) - likely to do with energy straggling?
* Investigating physics lists and in touch with Maestro o attempt to solve discrepancy (currently taking TOPAS as ground truth)


==== QuARC & QuADProBe Geant4 Simulations ====
==== QuARC & QuADProBe Geant4 Simulations ====


* Get Saads QuARC G4 simulation working  
* Improve statistics for photon output using PD sized scoring arrays (20 mil histories still not enough) or other options at filtering the photon output.
* Look at QuADProBe simulation from Raffy.
* Start looking at QuADProBe fibre simulation.
 
=== QuADProBe - Fibres ===
 
==== 1st prototype measurements (with Zybo + NI) ====
 
* Continue to work with Raffy on optimising analysis code.
* Analyse the data from Trento beam test nights 2 and 3.
** Correlate position measurements with QuARC.
* Get film data from Enrico and analyse to compare to fibres.
* Maybe duplicate setup at UCL, if need to establish calibration using LED or laser?
* Get beam data from Trento from Enrico.
 
==== Preparations for 2nd Prototype with Digital Readout ====
 
* Hamamatsu making S17285-128G digital readout photodiode arrays with samples expected to be ready in September 2025 - awaiting quotation from Kirsty.
* Comparison and between the two PD array options: S11865-128 (analogue readout) and S17285-128G (digital readout). Work out which has the better dynamic range and requires the most FPGA signals to control (still in progress).
* Assist with design of new front end board for S17285-128G digital readout photodiode arrays and obtain information from Hamamatsu about specific signal requirements.
 
=== QuARC ===
 
==== Dual-sided readout analysis ====
 
* Analyse the data from Trento beam test nights 1 and 2.
** Correlate position measurements with fibres.
* Continue Sonia's analysis from PPTC and UCLH.
 
=== Conference Abstracts ===
 
* PTCOG abstract submission open
 
=== Conference Talks ===
 
=== Papers ===
 
* Start preparations for paper on PPTC/UCLH/TIFPA beam tests - figure out scope and main points to cover. Possible journals: phiRO/PMB/MedPhys/Physica Medica
 
 
== Completed ==
 
=== MC Simulations ===
==== Dose Reconstruction ====
* TOPAS Simulations fully working on cluster and used to reconstruct 3D dose distributions from QuADProBe UCLH Beam Test 2024 for frontiers paper.
* FRED-MC working on old MacBook Air (2020) intel processor and matches TOPAS simulations. Doesn't run on new MacBook Pro as not compatible with apple silicon.
 
==== QuARC & QuADProBe Geant4 Simulations ====
 
* Saads QuARC G4 simulation working and added scoring onto left and right sides
* Get QuARC G4 simulation working with most recent G4 and have PD sized scoring area.


=== Fibres ===
=== Fibres ===


* Consider potential ways of calibrating fibre to PD coupling.
* Had two meetings with Blake Leverington and Julian Horne from Heidelberg on replicating/adapting the design of the frontend readout system of their fibre array monitor.
** Using Geant4 sim?
* Have so far received assembly drawings, technical description booklet, schematics and slides.
** Scanning diode or uniform light source?
* Investigate from Heidelberg SciFi readout setup and HSMC pin configurations what each of the signals do and how they get inputted in to the FPGA (on one end) and ADCs (on the other).
* Hassle Simon about Hamamatsu PD arrays !!!
* Understand Raffy's fibre readout for Trento beam test (will discus when she visits in September) - operated fibre readout with zybo and NI on DAQ express on behalf of raffy.
* Prepare slides about DAQ systems for existing fibre / fibre array detectors
 
=== QuARC ===


* Learn from Sonia how to operate the QuARC and diagnose any hardware and software issues ahead of Trento beam test in September.


=== Conference Abstracts ===
=== Conference Abstracts ===


* PTCOG - decided not to submit for standard but possibility of late breaking if have beam test beforehand
 
* PPRIG - submitted
=== Conference Talks ===
 
* Talk given at PPRIG 03/05


=== Papers ===
=== Papers ===


* Possible paper on UCLH beam test MC reconstructions?
* Submitted QuADProBe PSQA paper for Frontiers in Oncology special edition: Technology Developments in Proton Therapy and revised version following review on 07/08.

Latest revision as of 18:09, 7 October 2025

To Do

MC Simulations

Dose Reconstruction

  • If looking to use FRED - need to get installed on Plus1 or over Hypatia cluster for GPU processing capabilities (need training in Hypatia cluster first)

QuARC & QuADProBe Geant4 Simulations

  • Improve statistics for photon output using PD sized scoring arrays (20 mil histories still not enough) or other options at filtering the photon output.
  • Start looking at QuADProBe fibre simulation.

QuADProBe - Fibres

1st prototype measurements (with Zybo + NI)

  • Continue to work with Raffy on optimising analysis code.
  • Analyse the data from Trento beam test nights 2 and 3.
    • Correlate position measurements with QuARC.
  • Get film data from Enrico and analyse to compare to fibres.
  • Maybe duplicate setup at UCL, if need to establish calibration using LED or laser?
  • Get beam data from Trento from Enrico.

Preparations for 2nd Prototype with Digital Readout

  • Hamamatsu making S17285-128G digital readout photodiode arrays with samples expected to be ready in September 2025 - awaiting quotation from Kirsty.
  • Comparison and between the two PD array options: S11865-128 (analogue readout) and S17285-128G (digital readout). Work out which has the better dynamic range and requires the most FPGA signals to control (still in progress).
  • Assist with design of new front end board for S17285-128G digital readout photodiode arrays and obtain information from Hamamatsu about specific signal requirements.

QuARC

Dual-sided readout analysis

  • Analyse the data from Trento beam test nights 1 and 2.
    • Correlate position measurements with fibres.
  • Continue Sonia's analysis from PPTC and UCLH.

Conference Abstracts

  • PTCOG abstract submission open

Conference Talks

Papers

  • Start preparations for paper on PPTC/UCLH/TIFPA beam tests - figure out scope and main points to cover. Possible journals: phiRO/PMB/MedPhys/Physica Medica


Completed

MC Simulations

Dose Reconstruction

  • TOPAS Simulations fully working on cluster and used to reconstruct 3D dose distributions from QuADProBe UCLH Beam Test 2024 for frontiers paper.
  • FRED-MC working on old MacBook Air (2020) intel processor and matches TOPAS simulations. Doesn't run on new MacBook Pro as not compatible with apple silicon.

QuARC & QuADProBe Geant4 Simulations

  • Saads QuARC G4 simulation working and added scoring onto left and right sides
  • Get QuARC G4 simulation working with most recent G4 and have PD sized scoring area.

Fibres

  • Had two meetings with Blake Leverington and Julian Horne from Heidelberg on replicating/adapting the design of the frontend readout system of their fibre array monitor.
  • Have so far received assembly drawings, technical description booklet, schematics and slides.
  • Investigate from Heidelberg SciFi readout setup and HSMC pin configurations what each of the signals do and how they get inputted in to the FPGA (on one end) and ADCs (on the other).
  • Understand Raffy's fibre readout for Trento beam test (will discus when she visits in September) - operated fibre readout with zybo and NI on DAQ express on behalf of raffy.

QuARC

  • Learn from Sonia how to operate the QuARC and diagnose any hardware and software issues ahead of Trento beam test in September.

Conference Abstracts

Conference Talks

  • Talk given at PPRIG 03/05

Papers

  • Submitted QuADProBe PSQA paper for Frontiers in Oncology special edition: Technology Developments in Proton Therapy and revised version following review on 07/08.
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