ENLIGHT2018

Planning details for the 2018 ENLIGHT meeting and training day, hosted by UCL.

To-Do List

Chairs

• Ask Manchester/Christie what topics they would like to contribute: GR.
• Find out whether Ran Mackay would be willing to be an agent provocateur for one of the panel discussions: GR.
• Ask vendors what sponsorship they are willing to provide and what they want in return: RA.
• Discuss site visit with UCLH/Bouygues: RA.
• Arrange discussion session topics and speakers: RA, GR.
• Formal invitation letter (save the date letter without details, plus specific invitation to speakers): GR.
• Arrange monthly meetings with Local Organisers: GR, SJ.
• Arrange catering: SJ, Mohini Nair. — Mohini confirms this needs to be done closer to the time so we know numbers and dietary requirements.
• Obtain contact details for Hakan Nystrom: SJ.

Local Organiser Tasks

• Can we use the British Museum for reception on Monday 25^th?
• Find suitable location for formal dinner on Tuesday 26^th:
  • British Museum.
  • Thames riverboat.
  • Indian restaurant: Brick Lane, Tayyabs.
• Accommodation for delegates.
• Travel for delegates.
• Find out what local organisation necessary for previous conferences.

• Local point of contact: TBA...
• Industry contact: Richard Amos
• Evening entertainment: Megan Wilson
• Room bookings: Mohini Nair
• Hotel booking: Anastasia Basharina-Freshville
• Website information: Laurent Kelleter
• Oyster cards: TBA...

Completed

• Email Manjit Dosanjh/Cai Grau about meeting dates to confirm: SJ. — ✓
• Finalise timetable for all 3 days by mid-November: All. — ✓
• Book Cruciform Building Lecture Theatre for all 4 days: SJ. — ✓ — Mohini Nair has booked Cruciform LT for 3 days, 4 cluster rooms for Monday, will book other LT for EPTN meeting.
• Identify Local Organising Committee: SJ, GR. — ✓
• Find out if we can publish contributed papers in peer-reviewed journal special edition: SJ. — ✓ (Manjit Dosanjh prefers not to publish in a journal).
• Put together web page (use HEP website) including Indico page: SJ. — ✓ — Indico page already created by CERN: they want to host the pages. We won't have edit rights.
• Check how much funding is available from CERN and Manjit Dosanjh: SJ. — ✓ — Manjit Dosanjh suggests total cost of €20–30k split 50/50 with CERN, so €15k from CERN.
• Check with Manjit Dosanjh about poster session and prizes: SJ. — ✓ — Manjit Dosanjh confirmed 23/01/18 that 1 hour session required for Wednesday afternoon for 4 talks for poster prize winners, but no actual prize. Need to organise poster boards.
• Should industrial sponsors fund lunches and evening reception? — ENLIGHT committee preferred minimal sponsorship (we are not PTCOG).
• Put together detailed list of speakers and topics for each session by 28/07/17: All. — Sessions confirmed by ENLIGHT committee.
• Email suggestions for 3 speakers for each session, then forward to ENLIGHT Committee by 31/01/18: All. — ✓

Provisional Dates: Monday 25^th–Thursday 28^th June 2018

Training Day

Monday 25^th

ENLIGHT Meeting

Tuesday 26^th–Wednesday 27^th

EPTN Meeting

Thursday 28^th

UCLH PBT Site Visit

During ENLIGHT Meeting on Tuesday

Local Organising Committee

Chairs

Richard Amos, Simon Jolly, Gary Royle.

Local Support

Kate Ricketts, Stacey Holloway, Laurent Kelleter, Anastasia Basharina-Freshville, Megan Wilson, Mohini Nair

Training Day

Clinical Proton Delivery: How to design a PBT centre

Organiser: Kate Ricketts, Stacey Holloway.

Monday 25^th June, 09.30–18.00

Location: Cruciform Lecture Theatre

• Commercial vendors: Varian (TPS software and equipment hardware)

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Training Day ENLIGHT 2018

8.30am - 9am Registration and coffee

DIDACTIC SESSION

9.00 – 9.30 am (including Q&A) Lecture 2: Clinical Oncologist – Potential of protons (Yen-Ching Chang)

9.30 – 10.30am (including Q&A) Lecture 1: Technology and infrastructure of a clinical proton therapy centre (Richard Amos)

10.30-11.00am COFFEE

Workshop 1 11.00-12:30 Design and build of UCH Proton Centre (UCLH led session, Tahir Ahmed, Paulina Zakrzewska, Bouygues)

Learning outcome: Understanding the unique requirements in terms of architecture, build and infrastructure of a clinical proton therapy centre. Learning objectives: 1. Architectural insights from UCLH experience 2. Build techniques deployed at the UCH centre, BIM modelling 3. Infrastructure requirements for a clinical centre

12:30-13:30 LUNCH

Workshop 2 13:30 – 15:15 Proton treatment planning (Varian led session, Computer Cluster room) Learning outcome: understanding the difference in planning evaluation of protons compared to x-rays Learning objectives: 1. Impact and handling of range uncertainty 2. CTV optimisation vs PTV optimisation: Robust optimisation 3. Robust evaluation: Matthew Lowe (Manchester)?

15:15 – 15:30 COFFEE

Workshop 3 15:30 - 17:15 Clinical Trials in Proton Therapy (CTRAD led session, Johnny Lee) Learning outcome: Design, implementation and assessment of proton clinical trials Learning Objectives: 1. Design and challenges of proton vs photon trials 2. Patient perspective – PPI rep of CTRAD 3. Understanding the role of quality assurance – RTTQA. Output data variance, Johnny to bring previous data. 4. Big data platforms / evaluation

17:15-17:30 Wrap up

17:30 CLOSE

To do:

• Stacey email Varian, CTRAD
• Kate email Yen, Richard and Tahir Ahmed/Paulina Zakrzewska/Bouygues
• Mohini: book lecture theatre and cluster rooms. — ✓ — Mohini Nair has booked Christopher Ingold Building G20, Cruciform Building B1.15A, Foster Court B29 and Gordon Street (25) 105 Public Clusters for 12.00–16.00 for Monday 25th.

ENLIGHT Meeting

Tuesday 26^th–Wednesday 27^th June, 09.00–18.00

Location: Cruciform Lecture Theatre

Schedule

Each session approx. 2 hours with a 1 hour discussion session scheduled for before lunch.

Tuesday 26th

09:00-09:30	—	Welcome
09:30–11:00	—	Dosimetry Session
11:00–11.30	—	Coffee
11:30–12:30	—	Imaging Session pt.1
12:30–14:30	—	Lunch / Site Visits
14:30–15:30	—	Imaging Session pt.2
15:30–16:00	—	Coffee
16:00–18:00	—	Patient Selection Session

Wednesday 27th

09:00–11:00	—	Light Ions Session (including Treatment possibilities and limitations with fixed beamlines)
11:00–11:30	—	Coffee
11:30–12:45	—	Proton Immunotherapy
12:45–14:00	—	Lunch
14:00–15:00	—	Poster prize winners session.
15:00–15:30	—	Coffee
15:30–17:30	—	Paediatrics Session
17:30–18:00	—	ENLIGHT 2019 Announcement and Close

Tuesday 26th June

Location: Cruciform Lecture Theatre

09:00–09:30: Welcome

Organiser: GR

• Manjit Dosanjh - Introduction.
• Update on the UK proton service.

09:30–11:00: Dosimetry

Organiser: SJ

• Chairs: Rebecca Nutbrown, Ana Lourenco
• Hugo Palmans - Overview of the field.
• Stuart Green - IPEM code of practice.
• Andrzej Kacperek/Richard Amos - Clinical perspective.
• Simon Jolly - Range calorimeter.
• NPL (Russell Thomas) - Graphite calorimeter.
• Liverpool (Carsten Welsch/Jacinta Yap) - LHCb VELO for halo monitoring.

11.30–12.30: Imaging Session 1

Organiser: GR

• Chairs: David Hawkes, Catarina Veiga
• Hsiao-Ming Lu (MGH) - good but unlikely to come without budget - State of the art from a clinical perspective.
• Richard Amos - Clinical perspective.
• Joao Seco (HIT) - Current status from clinical perspective.
• Hugo Bouchard - Dual energy CT.
• Antje Knopf (Groningen) - Both clinical research, broad range of topics including 4D and TPS.
• Andy Boston - Prompt gamma.
• Simon Rit (Lyon) - Proton CT image reconstruction.

16:00–18:00: Patient Selection

Organiser: RA

• Chair: Stephanie Coombs, Ed Smith
• Adrian Crellin - UK overview.
• Holland - Dutch patient selection process.
• Stephanie Coombs - TBA.
• Karen Kirkby - MALTHUS, INSPIRE
• Bleddyn Jones
• Retreatment and clinical trials.

Wednesday 27th June

Location: Cruciform Lecture Theatre

09:00–11:00: Ion Beam Radiotherapy (including Treatment possibilities and limitations with fixed beamlines)

Organiser: SJ

• Chair: Stuart Green
• Radhe Mohan - Clinical perspective and future potential of ion beam radiotherapy.
• Marco Durante (CNAO) - Radiobiology of ion beams.
• Heidelberg/Dresden - Ion beam radiobiology.
• Markus Stock/Claus Schmitzer (MedAustron) - Status of MedAustron carbon line.
• Lanzhou (expensive...).
• Someone to speak on economics of ion beams.

11:30–12:45: Proton Immunotherapy Session

Organiser: GR.

• Chair: Rikky Sharma
• James Welch (MD Anderson) - Radiation/drug combinations for immune response.
• Sergio Quesada (UCL) - Immuno synergies with radiation.

12.45–14.00: Lunch

• Ran Mackay - Status of The Christie.

15:30–17:30: Paediatric Session

Organiser: RA

• Chair: Mark Gaze, Jenny Gains
• Beate Timmerman - Clinical overview.
• Yen-Ch'ing Chang - UK paediatric patient selection.
• Klaus Trott - Biological rationale for PBT treatment, neutron dose.
• David Grosshans/Anita Mahajan - Clinical case studies and outcomes for paediatrics.
• Case studies from European centres with treatment experience.

17:30–18:00: ENLIGHT 2019 Announcement and Close

Organiser: SJ

• EPTN Announcement
• ENLIGHT 2019 Announcement
• Closing address

EPTN Meeting

Location: AV Hill Lecture Theatre

Thursday 28^th June, 10:00–16:30